The major cities it traverses through would be (from south to north) Houma, Baton Rouge, roughly following Hwy 61 (Airline Hwy) to Natchez, Monroe, possibly El Dorado, Pine Bluff, and using I-530 to connect to Little Rock/Conway.
The route could continue north to Springfield, MO using U.S. 65's route.
The stretch of I-XX that would pass through our beloved Baton Rouge would be in the eastern part of the parish, giving the north side (Zachary, NBR, St. Francisville, etc) a faster connection to the city.
What do you all think about it? Do we need it? This could permanently replace the I-410 proposals that come up, while being cheaper for the city itself (not sure) and not encouraging sprawl like the loop would have done.
Keeping up with numbering rules, it would have to be either I-51 or I-53.
LA-AK stretch, each blue dot is representative of each of the major cities.

LA/MS stretch















